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SKF-83566-PEG1-pomalidomide

CAT: 0013-GTR19273833-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273833-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SKF-83566-PEG1-pomalidomide (Compound 8a) is an antitumor agent composed of SKF-83566, a dopamine D1 receptor antagonist, and Pomalidomide, an immunomodulator, linked via a covalent bond. It exhibits IC50 values of 5.5 μM and 10.13 μM against MDA-MB-231 and HeLa cells, respectively, and effectively inhibits cancer cell invasion, migration, and colony formation. Additionally, SKF-83566-PEG1-pomalidomide suppresses tumor growth and angiogenesis in the chick embryo chorioallantoic membrane (CAM) xenograft model using MDA-MB-231 cells. This compound is applicable in breast cancer research.
Storage Conditions
-20°C
Notes
For research use only.

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