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GSTO1-IN-6

CAT: 0013-GTR19273821-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273821-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSTO1-IN-6 is an allosteric covalent inhibitor of GSTO1 with an IC50 of 457 nM. It significantly reduces lipopolysaccharide (LPS) -induced secretion of IL-1β with an IC50 of 1.9 μM and IL-18 with an IC50 of 10 μM in human monocyte-derived macrophages. GSTO1-IN-6 covalently binds to GSTO1-Cys32, inducing conformational changes and protein instability. This compound is applicable in the study of inflammatory diseases.
Storage Conditions
-20°C
Notes
For research use only.

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