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WGU55

CAT: 0013-GTR19273801-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273801-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WGU55 is a selective and potent reversible type II transmembrane serine protease TMPRSS6 inhibitor with a Ki value of 12.15 nM. In KEK293 cells, WGU55 inhibits TMPRSS6 activity with an IC50 value of 138 nM. It displays a Ki value of 3510 nM for the homologous protease matriptase (SI=289) and a Ki value of 5.2 μM for the key coagulation protease factor Xa. WGU55 is applicable in the study of iron overload-related diseases, such as hereditary hemochromatosis.
Storage Conditions
-20°C
Notes
For research use only.

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