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LT-626

CAT: 0013-GTR19273784-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273784-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LT-626 is a potent PARP inhibitor with an IC50 of 1.60 nM. It effectively inhibits the synthesis of intracellular PAR, with an IC50 of 17.9 nM, and exhibits increased cytotoxicity in colorectal cancer cells harboring MRE11 mutations. In colorectal cancer cells, LT-626 shows synergistic effects when combined with Cisplatin, Oxaliplatin, and SN-38. This compound is applicable for studying colorectal cancer.
CAS Number
1207456-03-8
Smiles
CN1C ([C@H]2C=3C4=C (N[C@@H]2C5=CC=C (F) C=C5) C=C (F) C=C4C (=O) NN3) =NC=C1
Molecular Formula
C20H15F2N5O
Molecular Weight
379.37
Storage Conditions
-20°C
Notes
For research use only.

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