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TDPAM02

CAT: 0013-GTR19273690-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273690-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TDPAM02 is a positive allosteric modulator of the AMPA receptor GluA2. It specifically binds to the ligand-binding domain (LBD) of GluA2, with an IC50 of 1.4 nM for the GluA2 flop isoform. TDPAM02 stabilizes the activated conformation of the GluA2 receptor, delaying receptor inactivation or desensitization and maintaining rapid excitatory synaptic transmission in the central nervous system.
CAS Number
2231101-34-9
Smiles
O=S1 (=O) NCN (C2=CC (=CC=C21) CCC3=CC=C4C (=C3) N (CNS4 (=O) =O) C5CC5) C6CC6
Molecular Formula
C22H26N4O4S2
Molecular Weight
474.59
Storage Conditions
-20°C
Notes
For research use only.

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