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BCL6-760

CAT: 0013-GTR19273689-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273689-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BCL6-760 is an orally active BCL-6 PROTAC degrader with an EC50 of 0.8 nM. It selectively degrades BCL6 without affecting other CRBN substrates. Significant efficacy was demonstrated by BCL6-760 in an OCI-LY-1 tumor xenograft mouse model. This compound is applicable in diffuse large B-cell lymphoma (DLBCL) research.
CAS Number
3084696-50-1
Smiles
O=C1NC (=O) C (C2=NN (C=3C=C (C=CC32) N4CCC (N (C5=NC=C (Cl) C (=N5) NC6=CC=C7C (=C6) N (C (=O) N7C) CCC (O) (C) C) C) CC4) C) CC1
Molecular Formula
C36H43ClN10O4
Molecular Weight
715.26
Storage Conditions
-20°C
Notes
For research use only.

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