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Methocinnamox

CAT: 0013-GTR19273631-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273631-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Methocinnamox (M-CAM) is a selective μ-opioid receptor (MOR) antagonist with a Ki of 0.6 nM, known for its long-lasting receptor binding. Its extended activity results from non-covalent attachment to the MOR orthosteric site, which leads to prolonged receptor blockade requiring new receptor synthesis for function restoration. Additionally, Methocinnamox reversibly antagonizes κ-opioid receptors (KOR) (Ki = 4.9 nM) and δ-opioid receptors (DOR) (Ki = 2.2 nM) without exhibiting intrinsic agonistic activity. This compound can be utilized for reversing and preventing opioid overdose and use disorders.
CAS Number
117339-76-1
Smiles
N (C (C=CC1=CC=C (C) C=C1) =O) [C@]23[C@@]45C=6C (O[C@]4 (C (=O) CC2) [H]) =C (O) C=CC6C[C@]3 (N (CC7CC7) CC5) [H]
Molecular Formula
C30H32N2O4
Molecular Weight
484.6
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
SEA33976-01Methocinnamox

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