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RO5234444

CAT: 0013-GTR19273557-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273557-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RO5234444 is an orally active CCR2 antagonist, exhibiting an IC50 of 22 nM for human CCR2 and 161 nM for mouse CCR2. It mitigates glomerulosclerosis in a unilateral nephrectomy type 2 diabetes db/db mouse model, reduces proteinuria, and significantly improves glomerular filtration rate. RO5234444 is applicable for research in type 2 diabetic nephropathy.
CAS Number
1365266-79-0
Smiles
O[C@H]1C2 (CC2) CCN (CCCN3C (=O) [C@H] (C) N (C (C=CC4=CC (Cl) =C (F) C=C4) =O) CC3) C1
Molecular Formula
C24H31ClFN3O3
Molecular Weight
463.98
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-100819RO5234444

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