Products for Research Use Only

PI3Kα-IN-27

CAT: 0013-GTR19273556-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273556-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PI3Kα-IN-27 (Compound 50b) is an orally active PI3K-α inhibitor with an IC50 of 40 nM. It effectively inhibits PAK3, p110α, phosphorylated mTOR, and phosphorylated ERK1/2. PI3Kα-IN-27 can induce early apoptosis (Apoptosis) and demonstrates anticancer activity against pancreatic, lung, and breast cancers.
CAS Number
2098649-83-1
Smiles
O=C (NC1=CC=C (C=C1) CC) NC2CCN (C3=NC=4C=CSC4C (=N3) N5CCOCC5) CC2
Molecular Formula
C24H30N6O2S
Molecular Weight
466.6
Storage Conditions
-20°C
Notes
For research use only.