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DRAK1/2-IN-2

CAT: 0013-GTR19273550-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273550-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DRAK1/2-IN-2 (Compound Y17) is an inhibitor of DRAK1/2, with IC50 values of 353.2 nM for DRAK2 and 507.4 nM for DRAK1. This compound enhances mitochondrial membrane potential and glucose-stimulated insulin secretion (GSIS) . It also combats lipotoxicity-induced apoptosis and significantly suppresses the secretion of the pro-inflammatory cytokine IL-1β, providing anti-inflammatory effects. Additionally, DRAK1/2-IN-2 significantly reduces blood glucose levels in mice and is applicable in diabetes research.
Storage Conditions
-20°C
Notes
For research use only.

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