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AMPA receptor modulator-9

CAT: 0013-GTR19273991-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273991-01Size:10 mg
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Description
AMPA receptor modulator-9 is a selective, orally active positive allosteric modulator of AMPARs, capable of crossing the blood-brain barrier. It selectively enhances AMPAR activity in human and rat models, with an EC2x value of 0.96 μM in rat embryonic cortical primary neurons. The compound upregulates BDNF protein expression in primary rat cortical neuron cultures and enhances AMPA-mediated excitatory postsynaptic responses in rats and mice. AMPA receptor modulator-9 is applicable for cognitive disorder studies.
CAS Number
1204572-46-2
Smiles
O=S1 (=O) NCN (C2=CC (Cl) =C (Cl) C=C21) C3CC3
Molecular Formula
C10H10Cl2N2O2S
Molecular Weight
293.16
Storage Conditions
-20°C
Notes
For research use only.

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