Products for Research Use Only

BRD1172

CAT: 0013-GTR19273469-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273469-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BRD1172 (ML320) is a selective inhibitor of GSK3β, exhibiting an IC50 of 24 nM, demonstrating greater potency against GSK3β compared to CDK5. It significantly inhibits GSK3β-mediated Tau phosphorylation in SH-SY5Y cells and reduces the negative regulation by GSK3β on β-catenin degradation and TCF/LEF promoter activity. BRD1172 is applicable in research on Alzheimer's disease, cardiac hypertrophy, and cancer.
CAS Number
1597438-86-2
Smiles
C (F) (F) (F) C1=C2[C@@H] (C3=C (NC2=NN1) CC (C) (C) CC3=O) C4=C (OC) C=CC=C4
Molecular Formula
C20H20F3N3O2
Molecular Weight
391.39
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
HY-120917BRD1172

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