Products for Research Use Only

FP802

CAT: 0013-GTR19273418-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273418-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FP802 is a potent oral TwinF interface inhibitor capable of disrupting and neutralizing the toxicity of the NMDAR/TRPM4 death complex. Within the 5xFAD Alzheimer's disease (AD) mouse model, FP802 demonstrates significant neuroprotective effects, preventing cognitive decline, preserving neuronal structural integrity, reducing β-amyloid plaque formation, and mitigating mitochondrial damage. In the amyotrophic lateral sclerosis (ALS) mouse model, FP802 prevents motor neuron loss, lowers serum neurofilament light chain (NfL) levels, improves motor performance, and extends the lifespan of mice. FP802 can be utilized for research related to Alzheimer's disease and amyotrophic lateral sclerosis.
CAS Number
61694-81-3
Smiles
ClC1=CC=CC (=C1) CN (CC) CCN
Molecular Formula
C11H17ClN2
Molecular Weight
212.72
Storage Conditions
-20°C
Notes
For research use only.