Products for Research Use Only

AS2677131

CAT: 0013-GTR19273351-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273351-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AS2677131 is a potent and orally active PIKfyve inhibitor. It suppresses IL-12p40, IL-6, and IL-1β through the PIKfyve-c-Rel pathway and selectively inhibits the DNA-binding activity of c-Rel with IL-12p40 and IL-1β promoters. Additionally, AS2677131 represses the expression of MHCII molecules on B cells. This compound is applicable for research in inflammation and immunology, such as in arthritis.
CAS Number
2171502-44-4
Smiles
C (C) C=1C=2C (NC1C) =CC=C (C (NC=3C=C (C=NC3) C=4C=CC (=NC4) N5C[C@@H] (C) O[C@@H] (C) C5) =O) N2
Molecular Formula
C27H30N6O2
Molecular Weight
470.58
Storage Conditions
-20°C
Notes
For research use only.

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