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IKE16

CAT: 0013-GTR19273261-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273261-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IKE16 is a fungal-selective eukaryotic topoisomerase II inhibitor with an IC50 value of 13.68 μM. It selectively inhibits the DNA relaxation and decatenation activities of yTOPOII. IKE16 shows moderate activity against standard fungal strains [Candida albicans ATCC 10231, Saccharomyces cerevisiae ATCC 89763], with a minimum inhibitory concentration (MIC) of 2 μg/mL for S. cerevisiae ATCC 89763. It exhibits high cytotoxicity to human cells, with EC50 values of 0.07 μM in HepG2 cells and 0.045 μM in HEK-293 cells. IKE16 is utilized in antifungal infection research.
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
HY-178330IKE16

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