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WEE1-IN-14

CAT: 0013-GTR19273219-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273219-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WEE1-IN-14 (Compound 14) is a selective WEE1 inhibitor, with an IC50 of 0.5 nM determined by L-RB-FEP calculations and 1.0 nM in ADP-Glo​​ kinase assays. Inhibition of Wee1 in cancer cells disrupts the G2-M checkpoint, removing cell cycle regulation, leading to premature mitotic failure and subsequent tumor cell apoptosis. Thus, WEE1-IN-14 serves as a valuable tool for studying cancer biology.
CAS Number
2803921-87-9
Smiles
O=C1C2=CNC3=NC (=CC3=C2N (C) CN1C=4C (Cl) =CC=CC4Cl) C=5C=NN (C5) C6CCN (C) CC6
Molecular Formula
C25H25Cl2N7O
Molecular Weight
510.42
Storage Conditions
-20°C
Notes
For research use only.

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