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CQ3196

CAT: 0013-GTR19273164-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273164-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CQ3196 is an oral RIOK2 inhibitor with a Kd value of 14 nM. It effectively suppresses the ATPase activity of RIOK2, showing an IC50 value of 72 nM. CQ3196 also impedes cell proliferation and colony formation in gastric cancer cell lines, inducing apoptosis (apoptosis) in HGC-27 and AGS cells. Furthermore, CQ3196 inhibits downstream signaling pathways of RIOK2, reducing mTOR and AKT phosphorylation, while modulating ribosome function and protein synthesis. It inhibits tumor growth and can be utilized in both in vivo and in vitro studies of gastric cancer.
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
HY-175733CQ3196

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