RANKL-IN-1

CAT: 0013-GTR19273060-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19273060-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

RANKL-IN-1 is a selective inhibitor of receptor activator of nuclear factor-κB ligand (RANKL), with a KD value of 7.6 μM. It shows inhibitory activity and selectivity in osteoclastogenesis, with an IC50 of 0.07 μM and a selectivity index (SI) of 82.57. By directly binding to RANKL, RANKL-IN-1 blocks the activation of RANKL-induced NF-κB and MAPK pathways. This compound is applicable in research on metabolic diseases such as osteoporosis.

Storage Conditions

-20°C

Notes

For research use only.

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RANKL-IN-1

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