PD-166285

CAT: 0013-GTR19273042-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19273042-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PD-166285 is an inhibitor of PKMYT1 with an IC50 value of 17 nM. It exhibits potent antiproliferative effects on CCNE1-amplified OVCAR3 cells (IC50 = 0.14 μM) and HCC1569 cells (IC50 = 0.21 μM) . PD-166285 can induce apoptosis and cause CCNE1-amplified HCC1569 cells to arrest at the G1/S phase of the cell cycle. This compound is applicable for research on PKMYT1-targeted CCNE1-amplified cancers.

CAS Number

717094-37-6

Smiles

O=C1C (=CC=2C=NC (=NC2N1C) NC3=CC=C (OCCN (C) C) C=C3) C4=C (Cl) C=CC=C4Cl

Molecular Formula

C24H23Cl2N5O2

Molecular Weight

484.38

Storage Conditions

-20°C

Notes

For research use only.

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019157	PD-166285
FP26776-01	PD 166285
MBS6093810-01	PD-166285-d4
A13868-25	PD-166285 25mg
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A13868-10	PD-166285 10mg
B2094-25	PD-166285 dihydrochloride
A13868-50	PD-166285 50mg
A13868-1	PD-166285 1mg
A13868-5	PD-166285 5mg

PD-166285

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