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ER-464195-01

CAT: 0013-GTR19273029-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273029-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ER-464195-01 is an orally active inhibitor that targets the interaction between CRT and ITGAs. By disrupting the binding of CRT and ITGAs, ER-464195-01 reduces leukocyte infiltration and subsequent inflammatory cascade reactions. It downregulates the expression of pro-inflammatory genes induced by DSS, such as [TNF-α], [IL-1β], [IL-6], [IL-17f], and inhibits the phosphorylation of STAT3 and the production of serum amyloid A (SAA) . This compound is applicable for research in inflammatory bowel disease (IBD) .
CAS Number
859218-37-4
Smiles
Cl.C=1C=CC (=C (C1) N2CCN (CC2) CCC) C3CC (C) (C) CC (C) (C) C3
Molecular Formula
C23H39ClN2
Molecular Weight
379.03
Storage Conditions
-20°C
Notes
For research use only.

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