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AGW-11

CAT: 0013-GTR19273000-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273000-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AGW-11 is a potent dual inhibitor that targets EGFR (IC50 = 556 nM) and VEGFR2 (IC50 = 289.7 nM) . It induces apoptosis and inhibits the phosphorylation of EGFR, VEGFR2, and ERK1/2 in HUVECs. AGW-11 effectively suppresses cancer cell growth, reduces HUVEC proliferation, tube formation, and invasion, thus blocking angiogenesis. In 4T1 xenograft mouse models, AGW-11 significantly inhibits tumor growth and reduces lung metastasis. AGW-11 is applicable in breast cancer research.
Storage Conditions
-20°C
Notes
For research use only.

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