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JAK2-IN-14

CAT: 0013-GTR19272906-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272906-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK2-IN-14 is an orally effective JAK2 inhibitor with an IC50 of 2 nM. It exhibits selectivity for JAK2 over JAK1, JAK3, and TYK2 by factors of 89.5, 80.5, and 51 times, respectively. JAK2-IN-14 inhibits the STAT5 signaling pathway and can cause tumor cell cycle arrest and apoptosis (apoptosis) . It is applicable in the research of myeloproliferative neoplasms (MPN) .
CAS Number
3087335-24-5
Smiles
N1=CC (=C2NC1=NC=3C=CC (=C (OCCCCN4N=CC2=C4) C3) N5CCN (CC5) CC6CC6) C
Molecular Formula
C26H33N7O
Molecular Weight
459.6
Storage Conditions
-20°C
Notes
For research use only.

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