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SB405483

CAT: 0013-GTR19272826-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272826-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SB405483 is a CRBN (cereblon) orthosteric ligand-binding enhancer that promotes the ubiquitination and proteasomal degradation of CRBN substrates (such as CK1α, Wee1, and IKZF1/3) by stabilizing the CRBN protein conformation and enhancing its binding affinity for substrates. SB405483 can be used in cancer research, such as in multiple myeloma and acute myeloid leukemia.
Purity
99.70% (May vary between batches)
Smiles
O=C (NC1=C (O) C=C (C#N) C=C1) NC (N=CC=C2) =C2OCC3=CC=CC=C3
Molecular Formula
C20H16N4O3
Molecular Weight
360.37
Storage Conditions
-20°C
Notes
For research use only.

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