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Dichloro (bipyridine) platinum

CAT: 0013-GTR19272785-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272785-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dichloro (bipyridine) platinum is a potent platinum-based antitumor complex and a structural analogue of cisplatin. The incorporation of the bipyridine ligand enhances its lipophilicity and planar stacking ability. The compound interacts with DNA through covalent binding or intercalation, forming cis-Pt-DNA adducts that disrupt DNA replication and transcription. Research indicates that such complexes effectively activate pro-apoptotic signaling pathways and exhibit significant growth inhibition across various cancer cell lines, including those resistant to cisplatin. It serves as a foundational scaffold for developing next-generation metallodrugs in oncology.
CAS Number
13965-31-6
Purity
97.02% (May vary between batches)
Smiles
Cl[Pt]1 ([N]2=C (C3=[N]1C=CC=C3) C=CC=C2) Cl
Molecular Formula
C10H8Cl2N2Pt
Molecular Weight
422.17
Storage Conditions
-20°C
Notes
For research use only.

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