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LFM-A13

CAT: 0013-GTR19272747-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272747-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LFM-A13 is a highly selective inhibitor of the non-receptor tyrosine kinase BTK (Bruton's tyrosine kinase) (IC50 = 2.5 μM) . It irreversibly severs the downstream signaling network of the B-cell receptor (BCR) by targeted binding to the BTK kinase catalytic domain, exhibiting excellent anti-leukemic and immunomodulatory effects in models of acute/chronic lymphocytic leukemia and severe autoimmune diseases.
CAS Number
62004-35-7
Purity
99.50% (May vary between batches)
Smiles
N#CC (C (=O) NC1=CC (Br) =CC=C1Br) =C (O) C
Molecular Formula
C11H8Br2N2O2
Molecular Weight
360
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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B5952-5LFM-A13
SIH-461-25MGLFM A13

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