Products for Research Use Only

Losmapimod hydrochloride

CAT: 0013-GTR19272741-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272741-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Losmapimod hydrochloride (GW856553X) is an orally active, potent, and highly selective p38 alpha/beta MAPK inhibitor (IC50 = 0.8 nM) . It greatly reduces the release of pro-inflammatory cytokines, including TNF-alpha and IL-6, by blocking inflammatory signaling cascades, showing remarkable efficacy in COPD and severe cardiovascular inflammation models.
CAS Number
1246654-84-1
Purity
99.98% (May vary between batches)
Smiles
Cl.O=C (NCC (C) (C) C) C1=CN=C (C=C1) C=2C=C (C=C (F) C2C) C (=O) NC3CC3
Molecular Formula
C22H27ClFN3O2
Molecular Weight
419.92
Storage Conditions
-20°C
Notes
For research use only.

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