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ZIP14-IN-1

CAT: 0013-GTR19272731-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272731-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ZIP14-IN-1 is a selective inhibitor of ZIP14. It can significantly inhibit the activity of ZIP14, but has no significant effect on ZIP8 (SLC39A8) . ZIP14-IN-1 can effectively block the uptake of various divalent metal ions including zinc, iron, manganese and cadmium mediated by ZIP14. Its mechanism of action is to bind to the binding pocket formed at the dimer interface of ZIP14, thereby interfering with the metal ion transport pathway. In addition, ZIP14-IN-1 can reduce the levels of reactive oxygen species (ROS) and lipid peroxidation, alleviate metal-induced cytotoxicity, and can be used in related research on cancer cachexia .
CAS Number
1048-17-5
Purity
99.11% (May vary between batches)
Smiles
O=C1NCN (C=2C=CC=CC2) C13CCN (CCC=4C=CC=CC4) CC3
Molecular Formula
C21H25N3O
Molecular Weight
335.44
Storage Conditions
-20°C
Notes
For research use only.

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