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GSK702

CAT: 0013-GTR19277118-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277118-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK702 is a PROTAC and represents the less active cis- (S, S) -enantiomer of GSK983, a P300/CBP-associated factor (PCAF) and general control nonderepressible 5 (GCN5) PROTAC. It causes only minor reductions in PCAF protein levels. By binding to CRBN, GSK702 reduces IL-1β levels in macrophages and is useful for inflammation mediator research.
CAS Number
2260944-69-0
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2OCCCC4=CC=C (N (CCCN (C (=O) C5=CC=C (C=C5) [C@@H]6C[C@H] (NC7=C (Br) C (=O) N (C) N=C7) CN (C) C6) C) C) C=C4
Molecular Formula
C45H51BrN8O7
Molecular Weight
895.86
Storage Conditions
-20°C
Notes
For research use only.

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