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CP-17

CAT: 0013-GTR19274526-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274526-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CP-17 is a potent and selective inhibitor of IDH2/R140Q, with an IC50 value of 40.75 nM. It demonstrates over 55-fold selectivity for wild-type IDH2. In TF-1 (IDH2/R140Q) cells, CP-17 exhibits strong D-2-HG inhibitory activity and reverses the cell differentiation block caused by the R140Q mutation. CP-17 is applicable for research in acute myeloid leukemia (AML) .
CAS Number
1111233-06-7
Smiles
O=C (NC1=CC (=CC=C1N2CCCC2) NC (=O) C=3C=CC=CC3) NC4=CC (Cl) =CC=C4C
Molecular Formula
C25H25ClN4O2
Molecular Weight
448.95
Storage Conditions
-20°C
Notes
For research use only.

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