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SET-12

CAT: 0013-GTR19274403-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274403-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SET-12 is a highly active and selective antiparasitic agent against Leishmania amazonensis. It demonstrates outstanding activity against the promastigote form of the parasite, with an IC50 of 10.89 μM and a selectivity index (SI) of up to 12.1. Additionally, SET-12 is effective against intracellular amastigotes, with an IC50 of 3.81 μM and an SI that increases to 34.5. SET-12 also induces signs of apoptosis in the parasites, such as mitochondrial damage and the accumulation of reactive oxygen species (ROS) .
CAS Number
2241572-39-2
Smiles
C ([C@H] ([C@@H] (CCC1=CC=CC=C1) O) /C=C/CC) (=O) N2[C@@H] (C (C) C) COC2=O
Molecular Formula
C21H29NO4
Molecular Weight
359.47
Storage Conditions
-20°C
Notes
For research use only.

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