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Fusaric acid

CAT: 0013-GTR19269795-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19269795-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fusaric acid is an orally active multi-target inhibitor capable of inhibiting fibrosis-related signaling pathways such as NF-κB, TGF-β1/SMADs, and PI3K/AKT/mTOR. It also inhibits dopamine β-hydroxylase and reduces endogenous levels of norepinephrine and epinephrine. Fusaric acid activates apoptosis-related proteases such as Caspase-3/7, Caspase-8, and Caspase-9, thereby inducing oxidative stress and apoptosis. It chelates divalent metal cations, damages mitochondrial membrane structure, and exerts effects in improving myocardial fibrosis and alleviating cardiac hypertrophy. Additionally, it is applicable in research on esophageal cancer, liver cancer, and other conditions.
CAS Number
536-69-6
Smiles
O=C (O) C1=NC=C (C=C1) CCCC
Molecular Formula
C10H13NO2
Molecular Weight
179.22
Storage Conditions
-20°C
Notes
For research use only.

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