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Candidusin A

CAT: 0013-GTR19266389-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19266389-01Size:50 mg
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Description
Candidusin A (CHNQD-0803) (Compound 4) is an AMPK activator with a KD of 47.28 nM. This compound can be isolated from the marine fungus Aspergillus candidus. Candidusin A exhibits cytotoxic activity against human prostate cancer cells (22Rv1, PC-3, and LNCaP cells) and induces apoptosis. It reduces lipogenic gene expression and fat deposition, downregulates the NF-κB-TNFα inflammatory axis to suppress inflammation, and improves liver injury and fibrosis. Candidusin A is applicable in the study of non-alcoholic steatohepatitis (NASH) .
CAS Number
81474-59-1
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Smiles
OC=1C=CC (=CC1) C2=CC (OC) =C3C (OC4=CC (O) =C (O) C=C43) =C2OC
Molecular Formula
C20H16O6
Molecular Weight
352.34
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
TN11578-01Candidusin A

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