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Dichotomine C

CAT: 0013-GTR19266258-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19266258-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dichotomine C ((R) - (-) -Dichotomine C) is a β-carboline alkaloid with anti-allergic properties. It inhibits the release of β-hexosaminidase from RBL-2H3 cells with an IC50 of 62 μM. Additionally, it suppresses antigen IgE-mediated release of TNF-α and IL-4 in RBL-2H3 cells, with IC50 values of 19 μM and 15 μM, respectively. This compound is applicable in the research of type I hypersensitivity reactions.
CAS Number
755036-45-4
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research
Smiles
[C@@H] (CO) (O) C1=C2C (C=3C (N2) =CC=CC3) =CC (C (OC) =O) =N1
Molecular Formula
C15H14N2O4
Molecular Weight
286.28
Storage Conditions
-20°C
Notes
For research use only.

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