Talaroconvolutin A

CAT: 0013-GTR19266244-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19266244-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Talaroconvolutin A is an inducer of ferroptosis (ferroptosis) that operates by elevating reactive oxygen species (ROS) levels instead of acting through the GPX4 pathway. It decreases the expression of the solute carrier family 7 member 11 (SLC7A11) and increases the expression of arachidonate lipoxygenase 3 (ALOXE3) . This compound inhibits the growth of colorectal cancer cells HCT116 and bladder cancer cells SW480, with IC50 values of 1.22 μM and 1.4 μM, respectively. Talaroconvolutin A is applicable in studies related to colorectal and bladder cancers.

CAS Number

273199-42-1

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction

Smiles

C (=O) ([C@H]1[C@]2 ([C@] (C) (C=C (C) [C@H]1\C (=C\[C@H] (CC) C) \C) C[C@H] (C) CC2) [H]) C3=C\C (=C\C4=CC=C (O) C=C4) \NC3=O

Molecular Formula

C32H41NO3

Molecular Weight

487.67

Storage Conditions

-20°C

Notes

For research use only.

Alternative Products

Catalog	Name
HY-N15742	Talaroconvolutin A

Talaroconvolutin A

Alternative Products

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