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Lipid TD5

CAT: 0013-GTR19265831-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19265831-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lipid TD5, an ionizable cationic lipid (pKa = 7.3), is utilized in the creation of lipid nanoparticles (LNPs) for mRNA delivery both in vitro and in vivo. These LNPs are internalized via endocytosis in a serotonin (5-HT) receptor subtype 1A-dependent manner in primary mouse astrocytes. When administered intrathecally, LNPs containing lipid TD5 preferentially target the brain over the liver and spleen in mice.
Field of Research
Metabolism Research
Storage Conditions
-20°C
Notes
For research use only.

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