Products for Research Use Only

SCL-1

CAT: 0013-GTR19264617-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264617-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SCL-1 is an orally active anti-PD-1/PD-L1 inhibitor that disrupts the interaction between PD-1 and PD-L1. It enhances the numbers of T cells, B cells, and natural killer cells. SCL-1 exhibits potent tumor growth inhibitory effects by inducing effector T cells within the tumor and upregulating the expression of long non-coding RNAs as neoantigens, thereby activating cytotoxic T lymphocytes. SCL-1 is applicable in cancer research, including studies on triple-negative breast cancer.
CAS Number
1061105-16-5
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
O=C (N1CCCCC1C) C2CCN (C3=NN4C (=NN=C4C (F) (F) F) C=C3) CC2
Molecular Formula
C18H23F3N6O
Molecular Weight
396.41
Storage Conditions
-20°C
Notes
For research use only.