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Factor B-IN-6

CAT: 0013-GTR19264482-02Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264482-02Size:10 mg
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Description
Factor B-IN-6 is an orally bioavailable inhibitor of Factor B. It exhibits significant inhibitory activity on the activation of the human serum alternative pathway. In model animals, Factor B-IN-6 can improve kidney lesions and function, reducing urinary protein levels. Factor B-IN-6 is applicable for kidney disease research.
CAS Number
2797066-55-6
Field of Research
Immunology & Inflammation
Smiles
C (C1=C2C (=C (C) C=C1OC) NC=C2) N3[C@@H] (C[C@H] (CC3) [C@H]4CC (F) (F) C4) C5=CC=C (C (O) =O) C=C5
Molecular Formula
C27H30F2N2O3
Molecular Weight
468.54
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Zme8UP9jgy
CAS Number2797066-55-6
PubChem CID171414287
IUPAC Name4-[(2S,4S)-4-(3,3-difluorocyclobutyl)-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid
Molecular FormulaC27H30F2N2O3
Molecular Weight468.5
XLogP3.2
Topological Polar Surface Area65.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count34
Formal Charge0
Complexity721
SMILES
CC1=CC(=C(C2=C1NC=C2)CN3CC[C@@H](C[C@H]3C4=CC=C(C=C4)C(=O)O)C5CC(C5)(F)F)OC
InChI
InChI=1S/C27H30F2N2O3/c1-16-11-24(34-2)22(21-7-9-30-25(16)21)15-31-10-8-19(20-13-27(28,29)14-20)12-23(31)17-3-5-18(6-4-17)26(32)33/h3-7,9,11,19-20,23,30H,8,10,12-15H2,1-2H3,(H,32,33)/t19-,23-/m0/s1
InChIKey
HGEHJJJNMAFREE-CVDCTZTESA-N
Chemical Structure
2D Structure
2D structure of Zme8UP9jgy
CAS: 2797066-55-6
CID: 171414287
Formula: C27H30F2N2O3
MW: 468.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight468.5
XLogP33.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass468.22244915
Monoisotopic Mass468.22244915
Topological Polar Surface Area65.6 Ų
Heavy Atom Count34
Formal Charge0
Complexity721
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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MBS6404480-01IL-6 (B Cell stimulatory factor 2) (APC)
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