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Faridoxorubicin

CAT: 0013-GTR19264272-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264272-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Faridoxorubicin (AVA-6000) is a prodrug that targets fibroblast activation protein alpha (FAPα) . It releases active doxorubicin through FAPα-mediated cleavage, enhancing drug exposure within tumors while reducing cardiac toxicity. Faridoxorubicin holds potential for research in solid tumors, such as liver metastases from colorectal cancer.
CAS Number
1841402-73-0
Smiles
OC=1C2=C ([C@@H] (O[C@H]3C[C@H] (NC (=O) [C@H]4N (C ([C@H] (NC (=O) C=5C=CN=CC5) C) =O) CCC4) [C@H] (O) [C@H] (C) O3) C[C@@] (C (CO) =O) (O) C2) C (O) =C6C1C (=O) C=7C (C6=O) =C (OC) C=CC7
Molecular Formula
C41H44N4O14
Molecular Weight
816.81
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T211955-01Faridoxorubicin

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