HERG-IN-3

CAT: 0013-GTR19263877-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19263877-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

HERG-IN-3 is an orally active hERG inhibitor with an IC50 of 44.5 nM. It has a Ki value of 14 nM for the β2-adrenergic receptor. hERG-IN-3 exhibits skeletal muscle Nav1.4 sodium channel blocking activity with an IC50 of 4.4 μM, which is three times higher than that for hNav1.5. In animal models, hERG-IN-3 demonstrates potent antimyotonic activity and can be utilized in the study of congenital myotonia.

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Storage Conditions

-20°C

Notes

For research use only.

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HY-175289	HERG-IN-3
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sc-515611 P	HERG (F-3) P
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HY-163421	HERG-IN-2
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HERG-IN-3

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