Products for Research Use Only

FAK-IN-28

CAT: 0013-GTR19263764-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263764-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FAK-IN-28 is an orally active FAK inhibitor with an IC50 of 0.4 nM. It exhibits both antiproliferative and antimetastatic effects. FAK-IN-28 induces apoptosis by triggering caspase-3-dependent pathways through increased ROS levels. This compound effectively inhibits tumor growth without causing weight loss or hepatorenal toxicity. FAK-IN-28 is suitable for research on FAK-driven malignancies, including colon cancer, cervical cancer, triple-negative breast cancer, and melanoma.
Field of Research
Cardiovascular Research, Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.