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ATM-IN-2

CAT: 0013-GTR19263730-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263730-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATM-IN-2 is a selective, orally active ATM inhibitor with an IC50 of 4 nM. It demonstrates high kinase selectivity, being over 700 times more selective relative to PIKK family members. ATM-IN-2 exerts its anti-tumor effects and promotes apoptosis by inhibiting ATM phosphorylation and downstream signaling pathways (p53, H2AX) . It is applicable for research in solid tumors, such as colon cancer.
Field of Research
Cell Biology, Molecular Biology, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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