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NMT-IN-8

CAT: 0013-GTR19263562-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263562-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NMT-IN-8 (Compound Ex.129) is an orally active and highly selective N-myristoyltransferase (NMT) inhibitor with an IC50 value of less than 10 nM. It binds to the peptide binding pocket of NMT, blocking the enzyme-catalyzed protein N-myristoylation, thereby disrupting key pathways such as protein transport, signal transduction, and viral replication. NMT-IN-8 shows promise for research in oncology (including MYC-dependent cancers and B-cell lymphoma) and infectious diseases (such as malaria, HIV, and rhinovirus infections) .
CAS Number
2765258-26-0
Field of Research
Signal Transduction
Smiles
C (NC (=O) C1CN (C1) C2=NC (=NC=C2Cl) N3[C@@H] (C) CNCC3) (C) (C) C=4N5C (=NC4) C=CC=C5
Molecular Formula
C23H29ClN8O
Molecular Weight
468.98
Storage Conditions
-20°C
Notes
For research use only.

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