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RJG-2036

CAT: 0013-GTR19263477-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263477-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RJG-2036 is a potent covalent inhibitor of human prostaglandin reductase 2 (PTGR2) with an IC50 of 100 nM. It effectively inhibits NADPH-dependent reduction reactions, significantly reducing the secretion of inflammatory factors such as TNF-α and the release of various pro-inflammatory eicosanoids in LPS-stimulated THP-1 macrophages. RJG-2036 shows promise for research in inflammatory diseases.
CAS Number
2851993-73-0
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
O=C (C1=CC=CC (=C1) S (=O) (=O) N2N=CN=C2) N3CCN (C=4C=CC=CC4OC) CC3
Molecular Formula
C20H21N5O4S
Molecular Weight
427.48
Storage Conditions
-20°C
Notes
For research use only.

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