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DW34

CAT: 0013-GTR19263293-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263293-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DW34 is an orally bioactive pan-BRD4-D1-biased inhibitor that also exhibits BRD4-D2 activity. It demonstrates a low nanomolar inhibitory effect comparable to I-BET151 (EC50 value of 0.16 μM), with an EC50 value of 0.14 μM. DW34 significantly alleviates lipopolysaccharide (LPS) -induced liver inflammation and acetaminophen (APAP) -induced toxicity by reducing chemokine expression and cell necrosis.
CAS Number
2758171-54-7
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
N1=NN (C (C=2N=C (OC=3C=C (C=C (C3) C) C) C=CC2) =C1C) C4CCN (CCN (C) C) CC4
Molecular Formula
C25H34N6O
Molecular Weight
434.58
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-173564DW34

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