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Sheep Human C4 binding protein Antibody

CAT: 0013-GTR17700610Size: 1 mLDry Ice: NoHazardous: No
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CAT#:0013-GTR17700610Size:1 mL
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Description
Precipitating polyclonal sheep antiserum to human C4 binding protein. C4-binding protein is a plasma protein with a molecular weight of 500,000 and consists of 6 chains. Its concentration in serum is about 250 mg/ml. It is one of the inhibitors of the complement activation system. The protein combines up to six molecules of C4b at or near the C2 combining site and is thus preventing further association with C2. It has been isolated as a homogenous protein for use in the antiserum production. Freund's complete adjuvant is used in the first step of the immunization procedure.
UniProt
P04003
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Source
C4-binding protein is a plasma protein with a molecular weight of 500,000 and consists of 6 chains. Its concentration in serum is about 250 μg/ml. It is one of the inhibitors of the complement activation system. The protein combines up to six molecules of C4b at or near the C2 combining site and is thus preventing further association with C2. It has been isolated as a homogenous protein for use in the antiserum production. Freund’s complete adjuvant is used in the first step of the immunization procedure.
Field of Research
Epigenetics, Immunology
Form
Delipidated, heat inactivated, lyophilized, stable antiserum. No preservative added.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Host or Source
Sheep

UniProtKB · P04003

C4b-binding protein alpha chain

C4BPA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04003
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
C4BPA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
C4bp
EC number
—
Processing
Precursor
Secondary accessions
Q5VVQ8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Complement pathwayImmunityInnate immunity

PTM

Disulfide bondGlycoprotein

Domain

RepeatSignalSushi

Cellular component

Secreted

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