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NBTI 5463

CAT: 0013-GTR19263119-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263119-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NBTI 5463 is a bacterial type II topoisomerase (topoisomerase II) inhibitor with antimicrobial properties. It effectively inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli. By binding to topoisomerase II, NBTI 5463 prevents DNA cleavage and re-ligation, thereby impeding bacterial DNA replication and transcription. This compound shows potential for research into Gram-negative bacterial infections.
CAS Number
1227303-03-8
Field of Research
Infectious Disease & Virology, Molecular Biology
Smiles
C ([C@H] (N) [C@]1 (CC[C@H] (NCC=2N=C3C (=CC2) OCC (=O) N3) CC1) [H]) N4C=5C (C=CC4=O) =NC=C (OC) C5
Molecular Formula
C25H30N6O4
Molecular Weight
478.54
Storage Conditions
-20°C
Notes
For research use only.

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