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Sheep Human Factor I Antibody

CAT: 0013-GTR17700604Size: 1 mLDry Ice: NoHazardous: No
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CAT#:0013-GTR17700604Size:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Precipitating polyclonal sheep antiserum to human factor I. Factor I is a serine protease composed of two disulphide-linked chains. The protein has a molecular weight of 88.000 and its mean concentration in human plasma is 35 mg/ml. It is involved in the regulation of the C3/C5 convertase of either pathway. Using C4-binding protein or factor H splits the a chains of C4b or C3b respectively, which includes their roles in the C3/C5 convertases. It has been isolated as a homogenous protein for use in the antiserum production. Freund's complete adjuvant is used in the first step of the immunization procedure.
UniProt
P05156
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Factor I is a serine protease composed of two disulphide-linked chains. The protein has a molecular weight of 88.000 and its mean concentration in human plasma is 35 μg/ml. It is involved in the regulation of the C3/C5 convertase of either pathway. Using C4-binding protein or factor H splits the a chains of C4b or C3b respectively, which includes their roles in the C3/C5 convertases. It has been isolated as a homogenous protein for use in the antiserum production. Freund’s complete adjuvant is used in the first step of the immunization procedure.
Field of Research
Epigenetics, Immunology, Infectious Diseases
Form
Delipidated, heat inactivated, lyophilized, stable IgG fraction. No preservative added. Total protein and IgG concentration are comparable to those of pooled normal sheep serum. No foreign proteins added.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Host or Source
Sheep

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