Products for Research Use Only
RegisterLogin

Paclitaxel-2′-succinate NHS ester

CAT: 0013-GTR19262894-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19262894-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Paclitaxel-2′-succinate NHS ester is a derivative of paclitaxel featuring a succinate linker with its carboxyl group activated as an NHS ester. The NHS ester moiety exhibits high reactivity towards amino or hydroxyl groups, facilitating its conjugation with various molecules (such as peptides, proteins, antibodies, enzymes, or polymers) . This compound is utilized in the development of nanomedicines and cancer research.
CAS Number
245110-80-9
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O (C (C) =O) [C@]12[C@]3 ([C@H] (OC (=O) C4=CC=CC=C4) [C@@]5 (O) C (C) (C) C ([C@@H] (OC (C) =O) C (=O) [C@]3 (C) [C@@H] (O) C[C@]1 (OC2) [H]) =C (C) [C@@H] (OC ([C@@H] ([C@@H] (NC (=O) C6=CC=CC=C6) C7=CC=CC=C7) OC (CCC (ON8C (=O) CCC8=O) =O) =O) =O) C5) [H]
Molecular Formula
C55H58N2O19
Molecular Weight
1051.05
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Paclitaxel-2'-succinate N-hydroxysuccinimidyl ester
CAS Number245110-80-9
PubChem CID58755901
IUPAC Name1-O-[(1S,2R)-1-benzamido-3-[[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-2-benzoyloxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-15-yl]oxy]-3-oxo-1-phenylpropan-2-yl] 4-O-(2,5-dioxopyrrolidin-1-yl) butanedioate
Molecular FormulaC55H58N2O19
Molecular Weight1051.0
XLogP1.9
Topological Polar Surface Area291
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count19
Rotatable Bond Count21
Heavy Atom Count76
Formal Charge0
Complexity2350
SMILES
CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)OC(=O)CCC(=O)ON7C(=O)CCC7=O)O)OC(=O)C8=CC=CC=C8)(CO4)OC(=O)C)O)C)OC(=O)C
InChI
InChI=1S/C55H58N2O19/c1-29-35(72-51(68)45(73-40(63)24-25-41(64)76-57-38(61)22-23-39(57)62)43(32-16-10-7-11-17-32)56-49(66)33-18-12-8-13-19-33)27-55(69)48(74-50(67)34-20-14-9-15-21-34)46-53(6,36(60)26-37-54(46,28-70-37)75-31(3)59)47(65)44(71-30(2)58)42(29)52(55,4)5/h7-21,35-37,43-46,48,60,69H,22-28H2,1-6H3,(H,56,66)/t35-,36-,37+,43-,44+,45+,46-,48-,53+,54-,55+/m0/s1
InChIKey
DXNRHBJDAAJTTD-CGFZLWGJSA-N
Chemical Structure
2D Structure
2D structure of Paclitaxel-2'-succinate N-hydroxysuccinimidyl ester
CAS: 245110-80-9
CID: 58755901
Formula: C55H58N2O19
MW: 1051.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1051.0
XLogP31.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count19
Rotatable Bond Count21
Exact Mass1050.36337762
Monoisotopic Mass1050.36337762
Topological Polar Surface Area291 Ų
Heavy Atom Count76
Formal Charge0
Complexity2350
Isotope Atom Count0
Defined Atom Stereocenter Count11
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19154217-01Paclitaxel succinate NHS ester
GTR19273573-01Paclitaxel succinate sulfo-NHS ester
GTR19226757DBCO-NHS ester 2
GTR19209312-01Fluoxetine succinate ester
GTR19247978-01DOTAM-NHS-ester
GTR19315276-01MeCY5-NHS ester
GTR19269021-01NOTA-NHS ester
GTR19202867-01DOTA-​NHS-​ester
GTR19340601-01Cy3B NHS ester
GTR19203025-01TCO-NHS ester

Alternative Products

CatalogName
HY-164165-01Paclitaxel-2′-succinate NHS ester
RM-P812574-01Paclitaxel Succinate Nhs Ester
HY-17664Paclitaxel succinate sulfo-NHS ester
T71587-01Fluoxetine succinate ester
439344-017-Acetyl Paclitaxel Trichloroethyl Ester
S5328-60ASolifenacin Succinate ((1S) -3,4-Dihydro-1-phenyl-2 (1H) -isoquinolinecarboxylic acid (3R) -1-azabicyclo-[2.2.2]oct-3-yl ester succinate, (1S, 3’R) -3’quinuclidinyl-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate succinate)
MBS6064224-01Solifenacin Succinate ((1S) -3,4-Dihydro-1-phenyl-2 (1H) -isoquinolinecarboxylic acid (3R) -1-azabicyclo-[2.2.2]oct-3-yl ester succinate, (1S, 3'R) -3'quinuclidinyl-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate succinate)
467766-01Trandolaprilat 2-Benzyl Ester 1’-Methyl Ester
TRC-D473330-1G2,2-Dimethylcyclohexylphthalic Acid Ester
RG-A262749-012-Methylalanine Phenyl Ester

Popular Products