Products for Research Use Only
RegisterLogin

ICT10336

CAT: 0013-GTR19262717-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19262717-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ICT10336 is a hypoxia-reactive prodrug of the ATR inhibitor AZD6738. It specifically activates under hypoxic conditions in vitro, selectively releasing AZD6738. This action inhibits ATR activation at the T1989 and S428 phosphorylation sites, consequently disrupting HIF1a-mediated adaptation of hypoxic cancer cells and inducing cell death in both 2D and 3D cancer models. ICT10336 is also a metabolic substrate of CYPOR activity.
Field of Research
Molecular Biology, Signal Transduction
Molecular Formula
C32H40N10O7S
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T210166-01ICT10336

Popular Products