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Goat Human C1s Antibody

CAT: 0013-GTR17700599Size: 1 mLDry Ice: NoHazardous: No
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CAT#:0013-GTR17700599Size:1 mL
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Description
Goat polyclonal antibody to C1S.
UniProt
P09871
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Source
C1 component of human complement is a complex of three glycoproteins: C1q, C1r and C1s. C1s has a molecular weight of 83,000 and is present in plasma in an average concentration of 50 μg/ml, either as a complex with C1q and C1s or in the absence of C1q as a tetramer with C1s. The subcomponents of the C1 complex are responsible for the initiation of the classical pathway of complement activation. The subunit C1s is isolated as a homogenous protein for use in antiserum production. Freund’s complete adjuvant is used in the first step of the immunization procedure.
Field of Research
Cell Biology
Form
Delipidated, heat inactivated, lyophilized, stable whole antiserum No preservative added. Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal goat serum. No foreign proteins added.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Host or Source
Goat

UniProtKB · P09871

Complement C1s subcomponent

C1S_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09871
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
C1S
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.42
Processing
Precursor
Secondary accessions
D3DUT4, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

CalciumMetal-binding

Biological process

Complement pathwayImmunityInnate immunity

Disease

Disease variantEhlers-Danlos syndrome

PTM

Disulfide bondGlycoproteinHydroxylation

Domain

EGF-like domainRepeatSignalSushi

Molecular function

HydrolaseProteaseSerine protease

Cellular component

Secreted

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